Keith L. March, MD, PhD

Medical Director

1Dr. March is a Professor in the Department of Medicine, Cellular and Integrative Physiology and Biomedical Engineering, Indiana University School of Medicine. He directs the Indiana Center for Vascular Biology and Medicine, the Vascular and Cardiac Center of Adult Stem Cell Therapy, and the allied VA Center for Regenerative Medicine.

Dr. March has dedicated his career to bringing new medical approaches to patients. His publications include more than 110 manuscripts. He was editor of the first book dedicated to cardiovascular gene transfer. Dr. March’s research has resulted in more than 40 worldwide (23 U.S.) patents, with others pending. He invented the Closer, a suture-mediated closure device, used to close the puncture wound in an artery following heart catheterization, which is used in about 400,000 patients annually.

His laboratory focuses on vascular biology with particular emphasis on function and translational study of stem cells found in adipose tissue, which his laboratory identified as peri-vascular cells with critical roles in vasculogenesis, angiogenesis, and adipose tissue regulation. Dr. March is recognized as a leading expert in the field of adult stem cell research, particularly involving adipose-derived stromal stem cells. In 2008, he became Chair of the NIH/NHLBI DSMB that oversees cell therapy trials in the areas of heart, lung, and blood diseases.

In 2010, he established the VA Center for Regenerative Medicine at the Richard L. Roudebush VA Medical Center in Indianapolis; the first VA-sited Center dedicated specifically to moving adult stem cell therapies from the laboratory to patient care. In 2012, the Vascular and Cardiac Center of Adult Stem Cell Therapy / VA Center for Regenerative Medicine were selected by the National Institutes of Health along with six other partners throughout the US to lead the program of NIH-sponsored cardiovascular stem cell trials (the Cardiovascular Cell Therapy Research Network) in the US during the next seven years.

In addition to his research, Dr. March served as president of the International Federation of Adipose Therapeutics and Science (IFATS) and serves as the Chief Medical Advisor for the Cell Therapy Foundation. In both affiliations, he has worked to advance collaboration as well as awareness of stem cells.

 

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